Maltese Health Issues
Letter from the University of Sydney NSW Australia for Dr Geraldine Hunt - re Liver Shunt click on to read letter - Uni of Sydney - G Hunt
CONGENITAL PORTOSYSTEMIC SHUNTS IN MALTESE
Maltese have an increased prevalence of Congenital Portosystemic Shunts or CPS. The Maltese breed predisposition has been noted not only in
One of the first tests that can be suggested is measuring the Bile Acids in the blood. This is a simple test which measures the level of bile acids in the blood taken two hours after feeding. Maltese that return abnormal values need a follow up test to determine whether blood shunting is present.
Gameford Maltese (
Some of the Maltese tested readings.
Tattoo No Name Bile Acids Ammonia Tolerance (2)Pre Post
GFD068 GAMEFORD CANDA MAGIC - 47.37 - 30.0 - 20.0
GFD061 GAMEFORD JINNIVAH - 25.89 - 46.78 - 29.3
GFD042 CHERMERA CANDA MAGIC - 75.00 - 67.0 - 55.0
GFD014 JAMEBECO SIR ERICH - 98.79 - 48.78 - 78.51
GFD019 CH COSYVISTA PAGE BOY - 50.72 - 56.96 - 95.56
GFD018 PATRICIAN PRAEGO AMEE - 63.32 - 34.00 - 65.00
GFD017 WHITESILK LITTLE EGRET - 24.48 - 58.00 - 110.00
GFD601 CH SNOWDANCE THE COWBOY - 71.00 - 52.0 - 89.00
GFD066 MARBLANC TAILOR MAID - 75.00 - 44.93 - 54.68
GFD047 NADIFOME SWEET SUCCESS (Sister) - 125.0 - 62.0 - 52.00
GFD046 NADIFOME PROUD ONE (Litter sister) - 65.42 - 39.03 - 72.38
Ammonia Tolerance tests involve the following procedures:-
Enema (Microlax) to empty the rectum of faeces which could interfere with absorption of ammonia.
Pre-ammonia blood sample
Rectal administration of 2ml/kg of a 5% solution of ammonium chloride.
Post-ammonia blood sample 30 minutes later.
Ammonia is absorbed through the wall of the colon and into the portal vein (the vein that takes all the blood from the gastrointestinal tract in the liver). In normal dogs most of this ammonia is removed in the liver before the blood returns to the heart. It is expected therefore that the pre and post blood samples will have similar levels. This level is up to 50 umol/1 according to the laboratory normal range, but in practice as long as the increase is not large, value around 70 can be considered normal. In animals with portosystemic shunts, portal blood is able to bypass the liver so the ammonia is not broken down and it can be expected larger increases in post-ammonia levels.